Outpatient Clinic for Adult ADHD, Department of Psychiatry and Psychotherapy, University of Duisburg-Essen, LVR Clinic Essen; and daggerDepartment of Neurology, Alfried Krupp Hospital Essen, Essen, Germany. email@example.com
We present 3 new cases of psychotic symptoms in patients with adult attention-deficit/hyperactivity disorder while regularly treated with a stimulant therapy with methylphenidate.
Existing literature about this theme is reviewed, and potential mechanisms are discussed.
RESULTS AND CONCLUSIONS:
Medication with methylphenidate should be avoided in patients with vulnerability to schizophrenia and in drug addiction, but reported cases without these risk factors demonstrate that a careful and regular psychiatric monitoring is essential in all patients treated with methylphenidate.
- [PubMed – indexed for MEDLINE]