Normally, the virus is dormant, but if your immune system is weakened, either from disease or certain medications , it can become reactivated. EBV has been found to cause other diseases such as some cancers, multiple sclerosis, lupus, and others.
In a small subset of patients, EBV can manifest itself with prolonged symptoms similar to those of chronic fatigue syndrome. A diagnosis of chronic Epstein-Barr virus (CEBV) is usually made once symptoms persist for six months or more.
Chronic Epstein-Barr virus produces SYMPTOMS such as-
immobilizing fatigue, swollen, painful lymph glands, constant, sometimes unspecific pain possible in almost any part of the body, heart palpitations and occasionally irregular heart patterns, persistent nausea, lightheadedness with the possibility of fainting, inability to think clearly or concentrate( foggy head), pelvic pain, headaches and migraines, depression, fever and chills, hypersomnia and insomnia, sensitivity to light, swollen spleen and/or liver, tremors, and many others.
Due to the wide range of symptoms, diagnosing EBV and eventually CEBV is not easy, simply due to the fact that most physicians do not readily think of EBV as the cause and tend to skip the blood work necessary for its detection. Additionally, there is the compounding problem of the fact that some physicians do not believe that EBV is the root of the problem for the symptoms.