Neurological Manifestations of Uremic Encephalopathy Clinical Presentation


See the list below:

  • Uremic encephalopathy (UE) is a consequence of renal failure (RF).
  • Symptoms begin insidiously and are often noticed not by the patients but by their family members or caregivers.
  • In many cases, impairment of the nervous system provides the first indication of metabolic derangements.
  • Symptoms may progress slowly or rapidly.
  • Changes in sensorium include loss of memory, impaired concentration, depression, delusions, lethargy, irritability, fatigue, insomnia, psychosis, stupor, catatonia, and coma.
  • Patients may complain of slurred speech, pruritus, muscle twitches, or restless legs.

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