Multiple brain abscesses secondary to dental caries and severe periodontal disease.

Br J Oral Maxillofac Surg. 1988 Jun;26(3):244-7.


Department of Neurosurgery, Oldchurch Hospital, Romford, Essex.


A case is reported in which an intra-oral focus of sepsis is thought to have resulted in the patient developing multiple brain abscesses without the presence of lung infection or cardiac valvular disease. The link between the two sites of infection is supported by the isolation of two Streptococcus viridans species normally associated with dental caries and periodontal disease. The management of multiple brain abscesses is discussed.

Gen Dent. 1990 May-Jun;38(3):224-5.

Brain abscess secondary to dental infection.





[PubMed – indexed for MEDLINE]
Oral Dis. 2001 Jan;7(1):61-5.

Are dental infections a cause of brain abscess? Case report and review of the literature.


Newcastle upon Tyne NHS Trust, Dental Hospital and School, Richardson Road, Newcastle Upon Tyne, NE2 4AZ, UK.


Dental pathology and/or treatment have been linked to a small number of brain abscesses as possible sources of infection. A further case is presented, in which a dental site is implicated. A review of the evidence was undertaken. A wide range of dental procedures had been implicated. In some cases the brain isolate was not of dental origin. In many, the diagnosis was one of exclusion. In order to confirm the role of odontogenic infection in the pathogenesis of brain abscess, modern sampling techniques should be used to precisely identify the isolates. The causal organism should be identified in both oral and cranial sites.





[PubMed – indexed for MEDLINE]
J Craniomaxillofac Surg. 2007 Jan;35(1):63-7. Epub 2007 Feb 12.

Cerebral abscess of odontogenic origin.


Department of Oral and Maxillofacial Surgery, ‘Metropolitan’ Hospital, N. Faliro, Piraeus, Greece.



Cerebral abscess is a rare but serious and life-threatening infection. Dental infections have occasionally been reported as the source of bacteria for such an abcess.


A 54-year-old man was admitted with a right hemiparesis and epileptic fits. After clinical, laboratory and imaging examination, the diagnosis of a cerebral abscess of the left parietal lobe was made. The intraoral clinical examination as well as a panoramic radiograph confirmed the presence of generalized periodontal disease, multiple dental caries, and periapical pathology. The treatment included: (i) Immediate administration of high-dose intravenous antibiotics and (ii) surgical procedures consisting of craniotomy and resection of the abscess cavity first, and secondly removal of the periodontal, decayed and periapically involved teeth of the patient, in an effort to eradicate all the possible septic foci, presuming the cerebral abscess to be of odontogenic infection.


The patient made an uneventful recovery, and 29 months postoperatively he had completely recovered from the hemiparesis.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Oct;102(4):e21-3. Epub 2006 Aug 10.

Case report: brain and liver abscesses caused by oral infection with Streptococcus intermedius.


Department of Oral and Maxillofacial Surgery, University Hospital Freiburg, Freiburg, Germany.


Organ abscesses are a rare and life-threatening complication mostly of hematogenously disseminated infections. We report a case of brain and liver abscesses. Identification of the lesions was made by contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI), respectively. An oral examination comprised an oral focus of infection. Streptococcus intermedius was isolated from oral smear, liver and ventricular drainage, and blood sample. After the commencement of antibiotic therapy, drainage of abscesses and oral rehabilitation, complete recovery was noted.





[PubMed – indexed for MEDLINE]

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