Low-voltage EEG activity presenting from psychotic stage in a patient with anti-NMDA receptor encephalitis.

BMJ Case Rep. 2012 Oct 30;2012. pii: bcr2012007045. doi: 10.1136/bcr-2012-007045.

Source

Department of Neurology, Nara Medical University, Kashihara, Nara, Japan.

Abstract

EEG in anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis shows generalised or predominantly frontotemporal δ-θ activity, and epileptiform potentials are less frequent than slowness. The voltage of EEG activity in this disorder is uncertain. We studied the voltage pattern of EEG of two patients. Both patients had psychiatric symptoms, central hypoventilation requiring prolonged ventilatory support, seizures, involuntary movements and autonomic instability. No patient showed abnormal findings on conventional MRI. Mature teratoma was diagnosed in one patient after ovarian tumour resection. Both patients received corticosteroids and intravenous immunoglobulins, and plasmapheresis. One patient recovered completely. In one patient, teratoma was not found, and ventilatory support or sedative drugs were given for about 35 months. The EEG voltages in both patients were decreased in all brain areas as compared with those of the healthy controls. Low-voltage EEG activity in all brain areas was evident from the psychotic stage.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

Up ↑

%d bloggers like this: